I actually forgot my that my AVR is also in the mix!
Now, how hard is it to set up? It's done on your computer. You enter in your Devices (equipment). You set up the Activities: tell it what device should be on or off. what input/outputs when you want to watch TV/watch a movie/ watch Roku/watch AppleTV/etc. You save it and voila, you press one button and off you go. All the buttons on the Harmony do everything that all the buttons on all of the remotes that operate all of the equipment. The great thing is that it even knows that volume should control the AVR volume, channel up and down should control the H3, skip back and forward controls the H3, etc....
I know you know this pawdog, but you made it sound like it is a task to set up and I don't see it that way. Yeah, I have some neighbors that have one and it was a bit much for them, they barely can figure out how to change a channel
, so I set it up for them.