I remember that series, it was in 1993, Charlotte was a 6 seed and they beat Boston which was a 3 seed. It was remembered because one of Boston's players ended up dieing after that series.
There have been only 2 playoff series where an 8 seed beat a 1 seed. The first one was in 1994 where the 1 seed Seattle losing to 8 seed Denver, and in 1999 lockout season where the 1 seed Miami lost to the 8 seed New York Knicks (who made it all the way to the finals where they got trounced by the Spurs, which led to the Knicks to desperately resigning all thier players at rediculous salaries, which cause the Knicks payoff to spiral out of control, and led them to hire that idiot Isiah Thomas, where he made it even worse, only now they suck and they are over paid!)