Again, dealing with a high end builder, and I am going to have him install the in-walls; so it should not be a problem. Might mean I have a couple inches less space, but that's ok.
Basically when I get to the house I want to be able to just connect the surrounds, av hardware, and projector, and be able to go from there.
I am debating about the direction the door opens, but as long as it opens "out" I will be in good shape. You are right the door to the mechanical room will be closed most of the time.
I think the design she sent me looks good, and it gives me a nice place for my library (I am envisioning bookshelves on the wall adjacent to the bathroom, and on both sides of the window, with a comfortable reading chair in the middle. Again, down the road, as all this stuff costs way too much money, but in the end I am going to be setup pretty well.