Amplification should be avoided as much as possible, because with every amplifier comes some distortion. If you can make things work by using a heavier gauge cable, such as RG-11/U versus RG-6/U, it takes a much longer cable before the issue of needing amplification comes up. Think of unnecessary amplifiers as expensive fuses or possible monkey wrenches in your system. A lightning strike can truly make them into a disposable fuse!
If you are at the point of using 2 or more cheap in-line amplifiers cascaded in series, and are not in a position to replace the cable, I may have another answer. Holland Electronics made a 36 dB in-line amplifier, primarily for use with commercial distribution systems. One of these is much better than two inexpensive in-line devices that may get 18-20 dB on their own, but tend to distort when used multiple times in the same system.
I have a few of these in used but operating condition, and would be willing to part with one for a fraction of the original price. PM if you have questions about suitability of this device for your specific situation.