Remember, HD is somewhere around 8GB per hour.
When it was announced it was the biggest HDD out there.
And it's still clsoe to the biggest available - unless somebody's putting multiple 300GB drives into something - and that'd be BIG $$$.
But to answer your question, sure if you want to set it up - you got an HD-Tivo or some other HD-capable device with huge HDDs? The operative part of the question is "HD-capable", of course.